The Large-scale Medical Imaging Related Studies Directory

This is an online resource that provides succinct overviews and direct access to pivotal neuroimaging research. Aimed at researchers, academics, and enthusiasts, the directory compiles key studies exploring brain structure, function, and neurological disease progression. It stands as a hub for fostering collaboration, enhancing data transparency, and promoting scientific advancements in the field of neuroimaging.

Name Description Website
Alzheimer’s Disease Neuroimaging Initiative (ADNI) A multisite, longitudinal study aimed at validating biomarkers for Alzheimer’s disease (AD) clinical trials, tracking AD progression through clinical, imaging, genetic, and biospecimen markers across various stages from normal aging to dementia. ADNI
Connectome Coordination Facility (CCF) Houses and distributes public research data for a series of studies that focus on the connections within the human brain, known as Human Connectome Projects. CCF
Human Connectome Project (HCP) Gathers data from 1,200 healthy young adults to create a comprehensive “network map” of the healthy human brain, exploring individual variability in brain circuits. HCP
UK Biobank (UKB) A large-scale biomedical database and research resource containing de-identified genetic, lifestyle and health information, and biological samples from half a million UK participants. UKB
Adolescent Brain Cognitive Development Study (ABCD) The largest long-term research project in the United States focusing on brain development and child health, inviting 11,880 children aged 9-10 to participate. ABCD
Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Brings together researchers in imaging genomics to understand brain structure, function, and disease, based on brain imaging and genetic data. ENIGMA
All of Us Research Program A research program from the National Institutes of Health (NIH) aims to enroll one million or more people from across the U.S. to advance medical research. All of Us
Osteoarthritis Initiative (OAI) A multi-center, ten-year observational study involving men and women, aimed at providing resources to enhance the understanding of prevention and treatment of knee osteoarthritis. OAI
Philadelphia Neurodevelopmental Cohort (PNC) Centers on exploring the interplay between brain, behavior, and genetics, involving over 9,500 individuals from the greater Philadelphia area. PNC
Pediatric Imaging, Neurocognition, and Genetics (PING) A large repository of standardized measurements of behavioral and imaging phenotypes accompanied by whole genome genotyping acquired from typically-developing children. PING
National Lung Screening Trial (NLST) A randomized multicenter study comparing low-dose helical computed tomography (CT) with chest radiography in the screening of older current and former heavy smokers for early detection of lung cancer. NLST
Image & Data Archive (IDA) Offers tools for de-identification, integration, search, visualization, and sharing diverse neuroscience data. IDA
NIMH Data Archive (NDA) Offers an infrastructure that makes available human subjects data from hundreds of research projects across various scientific domains. NDA
Brain Image Library (BIL) A national public resource providing facilities for depositing, analyzing, sharing, and interacting with large brain image datasets. BIL
Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) A randomized, controlled trial conducted to determine if specific screening exams reduce mortality from these cancers, enrolling approximately 155,000 participants. PLCO
NeuroImaging Tools & Resources Collaboratory (NITRC) A free web-based resource that offers comprehensive information on neuroinformatics software and data. NITRC
The Cancer Genome Atlas (TCGA) A comprehensive effort to accelerate our understanding of the molecular basis of cancer through genome analysis technologies. TCGA
Brain Tumor Segmentation (BraTS) Challenge Since 2012, BraTS has focused on the generation of a benchmarking environment and dataset for the delineation of adult brain gliomas. BraTS
Neuroscience Multi-Omic Data Archive (NeMO) A data repository specifically focused on the storage and dissemination of omic data generated from the BRAIN Initiative, SCORCH consortium and other brain research projects. NeMO
Data Archive for the Brain Initiative (DABI) A shared repository for invasive neurophysiology data from the NIH Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative. DABI
OpenNeuro A free and open platform for validating and sharing BIDS-compliant MRI, PET, MEG, EEG, and iEEG data. OpenNeuro
OpenNeuroPet A collaborative database initiative aimed at standardizing PET imaging data acquisition, documentation, analysis, and archiving to enhance data sharing and facilitate research replication. OpenNeuroPet
Block and Object Storage Service & Database(BossDB) A volumetric database for 3D and 4D neuroscience data, focused on Electron Microscopy and X-ray Micro/Nano Tomography. BossDB
Distributed Archives for Neurophysiology DataIntegration (DANDI) A platform for publishing, sharing, and processing neurophysiology data. DANDI
Neuroelectromagnetic Data Archive and ToolsResource (NEMAR) An open access data, tools, and compute resource for finding, assessing and processing human NeuroElectroMagnetic data (EEG, MEG, iEEG) shared by its authors thru OpenNeuro.org. NEMAR